Carla Startin

Research output

Research output per year 2009 2019 2020 2021 2023

• 25 Article
• 1 Chapter
• 1 Letter
• 1 Review article

Research output per year

Research output per year

Search results

• 2023

  Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels

  Murray, A., Gough, G., Cindrić, A., Vučković, F., Koschut, D., Borelli, V., Petrović, D. J., Bekavac, A., Plećaš, A., Hribljan, V., Brunmeir, R., Jurić, J., Pučić-Baković, M., Slana, A., Deriš, H., Frkatović, A., Groet, J., O'Brien, N. L., Chen, H. Y. & Yeap, Y. J. & 25 others, Delom, F., Havlicek, S., Gammon, L., Hamburg, S., Startin, C., D'Souza, H., Mitrečić, D., Kero, M., Odak, L., Krušlin, B., Krsnik, Ž., Kostović, I., Foo, J. N., Loh, Y.-H., Dunn, N. R., de la Luna, S., Spector, T., Barišić, I., Thomas, M. S. C., Strydom, A., Franceschi, C., Lauc, G., Krištić, J., Alić, I. & Nižetić, D., 5 Jul 2023, (E-pub ahead of print) In: EBioMedicine. p. 104692

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome

  Mgaieth, F., Baksh, R. A., Startin, C. M., Hamburg, S., Hithersay, R., Pape, S., Zetterberg, H., Ashton, N. J., Tamayo-Elizalde, M., Saini, F., Idris, M., Consortium, T. L. & Strydom, A., 28 Apr 2023, (E-pub ahead of print) In: Alzheimers and Dementia.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The mismatch negativity as an index of cognitive abilities in adults with Down syndrome

  Saini, F., Masina, F., Wells, J., Rosch, R., Hamburg, S., Startin, C. & Strydom, A., 3 Jul 2023, (E-pub ahead of print) In: Cerebral Cortex.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Comparison of resting-state EEG between adults with Down syndrome and typically developing controls

  Hamburg, S., Bush, D., Strydom, A. & Startin, C., 14 Oct 2021, In: Journal of Neurodevelopmental Disorders. 13, 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

  LonDownS Consortium, Oct 2021, In: MOLECULAR PSYCHIATRY. 26, 10, p. 5789

  Research output: Contribution to journal › Article › peer-review

• Development of Dementia, Including Assessment and Interventions

  Startin, C., Zaman, S. & Strydom, A., 14 Jul 2021, The Oxford Handbook of Down Syndrome and Development. Burack, J. A., Edgin, J. & Abbeduto, L. (eds.). Oxford University Press (OUP)

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• The Association between Physical Activity and CAMDEX-DS Changes Prior to the Onset of Alzheimer’s Disease in Down Syndrome

  Pape, S. E., Baksh, R. A., Startin, C., Hamburg, S., Hithersay, R. & Strydom, A., 27 Apr 2021, In: Journal of Clinical Medicine. 10, 9

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2020

  Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome

  D'Souza, H., Mason, L., Mok, K. Y., Startin, C. M., Hamburg, S., Hithersay, R., Baksh, R. A., Hardy, J., Strydom, A. & Thomas, M. S. C., 28 Sept 2020, In: JAMA network open. 3, 9, p. e2018221

  Research output: Contribution to journal › Article › peer-review

• Health comorbidities and cognitive abilities across the lifespan in Down syndrome

  Startin, C. M., D’Souza, H., Ball, G., Hamburg, S., Hithersay, R., Hughes, K. M. O., Massand, E., Karmiloff-Smith, A., Thomas, M. S. C. & Strydom, A., 23 Jan 2020, In: Journal of Neurodevelopmental Disorders. 12, 4 (2020).

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndrome

  Hithersay, R., Baksh, R. A., Startin, C., Wijeratne, P. A., Hamburg, S., Carter, B. & Strydom, A., 23 Nov 2020, In: Alzheimers and Dementia.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.

  Alić, I., Goh, P., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, K., Koschut, D., Brunmeir, R., Yeap, Y., O'Brien, N., Groet, J., Shao, X., Havlicek, S., Dunn, N., Kvartsberg, H., Brinkmalm, G., Hithersay, R., Startin, C. & Hamburg, S. & 22 others, Phillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, J., Foo, J., Becker, D., Rostagno, A., Ghiso, J., Krsnik, Z., Šimić, G., Kostović, I., Mitrečić, D., Francis, P., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H. & Nižetić, D., 10 Jul 2020, In: MOLECULAR PSYCHIATRY.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Assessing general cognitive and adaptive abilities in adults with Down syndrome: a systematic review.

  Hamburg, S., Lowe, B., Startin, C., Padilla, C., Coppus, A., Silverman, W., Fortea, J., Zaman, S., Head, E., Handen, B., Lott, I., Song, W. & Strydom, A., 30 Aug 2019, In: Journal of Neurodevelopmental Disorders. 11, 20 (2019).

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years

  Hithersay, R., Startin, C. M., Hamburg, S., Mok, K. Y., Hardy, J., Fisher, E. M. C., Tybulewicz, V. L. J., Nizetic, D. & Strydom, A., 1 Feb 2019, In: JAMA Neurology. 76, 2, p. 152-160 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Cognitive markers of preclinical and prodromal Alzheimer's disease in Down syndrome

  Startin, C. M., Hamburg, S., Hithersay, R., Al-janabi, T., Mok, K. Y., Hardy, J. & Strydom, A., 1 Feb 2019, In: Alzheimers and Dementia. 15, 2, p. 245-257 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Comparison of Receptive Verbal Abilities Assessed Using the KBIT-2 and BPVS3 in Adults with Down Syndrome

  Startin, C. M., Hamburg, S. & Strydom, A., 17 Jan 2019, In: Frontiers in Psychology. 9, 2730.

  Research output: Contribution to journal › Article › peer-review

• Dynamic Causal Modeling of the Relationship between Cognition and Theta-alpha Oscillations in Adults with Down Syndrome.

  Hamburg, S., Rosch, R., Startin, C., Friston, K. & Strydom, A., 16 Mar 2019, In: Cerebral Cortex. 29, 5, p. 2279–2290 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease

  Startin, C. M., Ashton, N. J., Hamburg, S., Hithersay, R., Wiseman, F. K., Mok, K. Y., Hardy, J., Lleó, A., Lovestone, S., Parnetti, L., Zetterberg, H., Hye, A. & Strydom, A., 21 Mar 2019, In: Alzheimer's Research & Therapy. 11, 1, 26 (2019).

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Reply to "Down Syndrome Cognitive Marker's Significance in Alzheimer's Disease and Dementia Management".

  Startin, C., Hamburg, S., Hithersay, R., Al-Janabi, T., Mok, K., Hardy, J. & Strydom, A., 23 Aug 2019, In: Alzheimers and Dementia. 15, 9, p. 1238-1239

  Research output: Contribution to journal › Letter

• Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome.

  Startin, C., Lowe, B., Hamburg, S., Hithersay, R. & Strydom, A., 16 Apr 2019, In: FRONTIERS IN PSYCHIATRY.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Aging related cognitive changes associated with Alzheimer's disease in Down syndrome

  Firth, N. C., Startin, C. M., Hithersay, R., Hamburg, S., Wijeratne, P. A., Mok, K. Y., Hardy, J., Alexander, D. C. & Strydom, A., 20 May 2018, In: Annals of Clinical and Translational Neurology. p. 741-751

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

  Strydom, A., Heslegrave, A., Startin, C. M., Mok, K. Y., Hardy, J., Groet, J., Nizetic, D. & Zetterberg, H., 10 Apr 2018, In: Alzheimer's Research & Therapy. 10, 1, 39 (2018).

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  The relationship between sound-shape matching and cognitive ability in adults with Down syndrome.

  Hamburg, S., Startin, C. & Strydom, A., 2 Aug 2017, In: Multisensory research. 30, 6, p. 537–547 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2016

  Developing an Informant Questionnaire for Cognitive Abilities in Down Syndrome: The Cognitive Scale for Down Syndrome (CS-DS)

  Startin, C. M., Rodger, E., Fodor-Wynne, L., Hamburg, S. & Strydom, A., 6 May 2016, In: PLoS One. 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The importance of understanding individual differences in Down syndrome

  Karmiloff-Smith, A., Al-Janabi, T., D'Souza, H., Groet, J., Massand, E., Mok, K., Startin, C., Fisher, E., Hardy, J., Nizetic, D., Tybulewicz, V. & Strydom, A., 23 Mar 2016, In: F1000 Research.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome

  Startin, C. M., Hamburg, S., Hithersay, R., Davies, A., Rodger, E., Aggarwal, N., Al-Janabi, T. & Strydom, A., 15 Nov 2016, In: Wellcome Open Research.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2015

  Variation in the X-linked EFHC2 gene is associated with social cognitive abilities in males.

  Startin, C., Fiorentini, C., de Haan, M. & Skuse, D., 24 Jun 2015, In: PLoS One.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2010

  Fluoxetine reverses the memory impairment and reduction in proliferation and survival of hippocampal cells caused by methotrexate chemotherapy.

  Lyons, L., ElBeltagy, M., Umka, J., Markwick, R., Startin, C., Bennett, G. & Wigmore, P., 22 Dec 2010, In: Psychopharmacology. 215, p. 105–115 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2009

  Innervation of canine skin: an immunohistochemical study.

  de, M. M., Startin, C. & Jeffery, N., 12 Sept 2009, In: Vet Record. 165, 11, p. 314-318 5 p.

  Research output: Contribution to journal › Article › peer-review