Carla Startin

2021

Comparison of resting-state EEG between adults with Down syndrome and typically developing controls

Hamburg, S., Bush, D., Strydom, A. & Startin, C., 14 Oct 2021, In: Journal of Neurodevelopmental Disorders. 13, 1

Research output: Contribution to journal › Article › peer-review

Open Access

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Development of Dementia, Including Assessment and Interventions

Startin, C., Zaman, S. & Strydom, A., 14 Jul 2021, The Oxford Handbook of Down Syndrome and Development. Burack, J. A., Edgin, J. & Abbeduto, L. (eds.). Oxford University Press (OUP)

Research output: Chapter in Book/Report/Conference proceeding › Chapter

The Association between Physical Activity and CAMDEX-DS Changes Prior to the Onset of Alzheimer’s Disease in Down Syndrome

Pape, S. E., Baksh, R. A., Startin, C., Hamburg, S., Hithersay, R. & Strydom, A., 27 Apr 2021, In: Journal of Clinical Medicine. 10, 9

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome

D'Souza, H., Mason, L., Mok, K. Y., Startin, C. M., Hamburg, S., Hithersay, R., Baksh, R. A., Hardy, J., Strydom, A. & Thomas, M. S. C., 28 Sep 2020, In: JAMA network open. 3, 9, p. e2018221

Research output: Contribution to journal › Article › peer-review

Health comorbidities and cognitive abilities across the lifespan in Down syndrome

Startin, C. M., D’Souza, H., Ball, G., Hamburg, S., Hithersay, R., Hughes, K. M. O., Massand, E., Karmiloff-Smith, A., Thomas, M. S. C. & Strydom, A., 23 Jan 2020, In: Journal of Neurodevelopmental Disorders. 12, 4 (2020).

Research output: Contribution to journal › Article › peer-review

Open Access

Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndrome

Hithersay, R., Baksh, R. A., Startin, C., Wijeratne, P. A., Hamburg, S., Carter, B. & Strydom, A., 23 Nov 2020, In: Alzheimers and Dementia.

Research output: Contribution to journal › Article › peer-review

Open Access

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.

Alić, I., Goh, PA., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, KY., Koschut, D., Brunmeir, R., Yeap, YJ., O'Brien, NL., Groet, J., Shao, X., Havlicek, S., Dunn, NR., Kvartsberg, H., Brinkmalm, G., Hithersay, R., Startin, C., Hamburg, S., & 22 othersPhillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, JE., Foo, JN., Becker, DL., Rostagno, A., Ghiso, J., Krsnik, Z., Šimić, G., Kostović, I., Mitrečić, D., Francis, PT., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H. & Nižetić, D., 10 Jul 2020, In: MOLECULAR PSYCHIATRY.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Assessing general cognitive and adaptive abilities in adults with Down syndrome: a systematic review.

Hamburg, S., Lowe, B., Startin, C., Padilla, C., Coppus, A., Silverman, W., Fortea, J., Zaman, S., Head, E., Handen, B., Lott, I., Song, W. & Strydom, A., 30 Aug 2019, In: Journal of Neurodevelopmental Disorders. 11, 20 (2019).

Research output: Contribution to journal › Article › peer-review

Open Access

Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years

Hithersay, R., Startin, C. M., Hamburg, S., Mok, K. Y., Hardy, J., Fisher, E. M. C., Tybulewicz, V. L. J., Nizetic, D. & Strydom, A., 1 Feb 2019, In: JAMA Neurology. 76, 2, p. 152-160 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Cognitive markers of preclinical and prodromal Alzheimer's disease in Down syndrome

Startin, C. M., Hamburg, S., Hithersay, R., Al-janabi, T., Mok, K. Y., Hardy, J. & Strydom, A., 1 Feb 2019, In: Alzheimers and Dementia. 15, 2, p. 245-257 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Comparison of Receptive Verbal Abilities Assessed Using the KBIT-2 and BPVS3 in Adults with Down Syndrome

Startin, C. M., Hamburg, S. & Strydom, A., 17 Jan 2019, In: Frontiers in Psychology. 9, 2730.

Research output: Contribution to journal › Article › peer-review

Dynamic Causal Modeling of the Relationship between Cognition and Theta-alpha Oscillations in Adults with Down Syndrome.

Hamburg, S., Rosch, R., Startin, CM., Friston, KJ. & Strydom, A., 16 Mar 2019, In: Cerebral Cortex. 29, 5, p. 2279–2290 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease

Startin, C. M., Ashton, N. J., Hamburg, S., Hithersay, R., Wiseman, F. K., Mok, K. Y., Hardy, J., Lleó, A., Lovestone, S., Parnetti, L., Zetterberg, H., Hye, A. & Strydom, A., 21 Mar 2019, In: Alzheimer's Research & Therapy. 11, 1, 26 (2019).

Research output: Contribution to journal › Article › peer-review

Open Access

Reply to "Down Syndrome Cognitive Marker's Significance in Alzheimer's Disease and Dementia Management".

Startin, C., Hamburg, S., Hithersay, R., Al-Janabi, T., Mok, K., Hardy, J. & Strydom, A., 23 Aug 2019, In: Alzheimers and Dementia. 15, 9, p. 1238-1239

Research output: Contribution to journal › Letter

Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome.

Startin, CM., Lowe, B., Hamburg, S., Hithersay, R. & Strydom, A., 16 Apr 2019, In: FRONTIERS IN PSYCHIATRY.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Aging related cognitive changes associated with Alzheimer's disease in Down syndrome

Firth, N. C., Startin, C. M., Hithersay, R., Hamburg, S., Wijeratne, P. A., Mok, K. Y., Hardy, J., Alexander, D. C. & Strydom, A., 20 May 2018, In: Annals of Clinical and Translational Neurology. p. 741-751

Research output: Contribution to journal › Article › peer-review

Open Access

Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

Strydom, A., Heslegrave, A., Startin, C. M., Mok, K. Y., Hardy, J., Groet, J., Nizetic, D. & Zetterberg, H., 10 Apr 2018, In: Alzheimer's Research & Therapy. 10, 1, 39 (2018).

Research output: Contribution to journal › Article › peer-review

Open Access

2017

The relationship between sound-shape matching and cognitive ability in adults with Down syndrome.

Hamburg, S., Startin, CM. & Strydom, A., 2 Aug 2017, In: Multisensory research. 30, 6, p. 537–547 11 p.

Research output: Contribution to journal › Article › peer-review

2016

Developing an Informant Questionnaire for Cognitive Abilities in Down Syndrome: The Cognitive Scale for Down Syndrome (CS-DS)

Startin, C. M., Rodger, E., Fodor-Wynne, L., Hamburg, S. & Strydom, A., 6 May 2016, In: PLoS One. 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The importance of understanding individual differences in Down syndrome

Karmiloff-Smith, A., Al-Janabi, T., D'Souza, H., Groet, J., Massand, E., Mok, K., Startin, C., Fisher, E., Hardy, J., Nizetic, D., Tybulewicz, V. & Strydom, A., 23 Mar 2016, In: F1000 Research.

Research output: Contribution to journal › Review article › peer-review

Open Access

The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome

Startin, C. M., Hamburg, S., Hithersay, R., Davies, A., Rodger, E., Aggarwal, N., Al-Janabi, T. & Strydom, A., 15 Nov 2016, In: Wellcome Open Research.

Research output: Contribution to journal › Article › peer-review

Open Access

2015