Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism

Volker Behrends; Guro Giskeogard; Natalia Bravo-Santano; Michal Letek Polberg; Hector C Keun

doi:10.1007/s00204-018-2371-0

Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism

Volker Behrends, Guro Giskeogard, Natalia Bravo-Santano, Michal Letek Polberg, Hector C Keun

Research output: Contribution to journal › Article › peer-review

Abstract

© 2018, The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/

Original language	English
Pages (from-to)	341-353
Journal	Archives in Toxicology
Volume	93
DOIs	https://doi.org/10.1007/s00204-018-2371-0
Publication status	Published - 14 Dec 2018

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https://link.springer.com/article/10.1007%2Fs00204-018-2371-0Licence: CC BY

Volker Behrends
- Centre for Integrated Research in Life and Health Sciences
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title = "Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism",

abstract = "{\textcopyright} 2018, The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/",

author = "Volker Behrends and Guro Giskeogard and Natalia Bravo-Santano and {Letek Polberg}, Michal and Keun, {Hector C}",

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T1 - Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism

AU - Behrends, Volker

AU - Giskeogard, Guro

AU - Bravo-Santano, Natalia

AU - Letek Polberg, Michal

AU - Keun, Hector C

PY - 2018/12/14

Y1 - 2018/12/14

N2 - © 2018, The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/

AB - © 2018, The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/

U2 - 10.1007/s00204-018-2371-0

DO - 10.1007/s00204-018-2371-0

M3 - Article

SN - 1432-0738

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JO - Archives in Toxicology

JF - Archives in Toxicology

ER -

Acetaminophen cytotoxicity in HepG2 cells is associated with a decoupling of glycolysis from the TCA cycle, loss of NADPH production, and suppression of anabolism

Abstract

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Volker Behrends

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