Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine

Michail Leventopoulos; Holger Russig; Joram Feldon; Christopher R. Pryce; Jolanta Opacka Juffry

doi:10.1016/j.neuropharm.2008.12.005

Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine

Michail Leventopoulos, Holger Russig, Joram Feldon, Christopher R. Pryce, Jolanta Opacka Juffry

School of Life and Health Sciences

Research output: Contribution to journal › Article

Abstract

Early life stress is a risk factor in aetiology of depression. In rats, early life tress can lead to prodepressive biomarkers in adulthood. The present study in male Wistar rats investigated the effects of early life deprivation and fluoxetine on motivati

Original language	English
Pages (from-to)	692-701
Journal	NEUROPHARMACOLOGY
Volume	56
Issue number	3
DOIs	https://doi.org/10.1016/j.neuropharm.2008.12.005
Publication status	Published - 2009

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10.1016/j.neuropharm.2008.12.005

http://dx.doi.org/10.1016/j.neuropharm.2008.12.005

Cite this

@article{997d5a7be5114c8e8ac7f11260407942,

title = "Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine",

abstract = "Early life stress is a risk factor in aetiology of depression. In rats, early life tress can lead to prodepressive biomarkers in adulthood. The present study in male Wistar rats investigated the effects of early life deprivation and fluoxetine on motivati",

author = "Michail Leventopoulos and Holger Russig and Joram Feldon and Pryce, {Christopher R.} and {Opacka Juffry}, Jolanta",

year = "2009",

doi = "10.1016/j.neuropharm.2008.12.005",

language = "English",

volume = "56",

pages = "692--701",

journal = "NEUROPHARMACOLOGY",

issn = "0028-3908",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine

AU - Leventopoulos, Michail

AU - Russig, Holger

AU - Feldon, Joram

AU - Pryce, Christopher R.

AU - Opacka Juffry, Jolanta

PY - 2009

Y1 - 2009

N2 - Early life stress is a risk factor in aetiology of depression. In rats, early life tress can lead to prodepressive biomarkers in adulthood. The present study in male Wistar rats investigated the effects of early life deprivation and fluoxetine on motivati

AB - Early life stress is a risk factor in aetiology of depression. In rats, early life tress can lead to prodepressive biomarkers in adulthood. The present study in male Wistar rats investigated the effects of early life deprivation and fluoxetine on motivati

U2 - 10.1016/j.neuropharm.2008.12.005

DO - 10.1016/j.neuropharm.2008.12.005

M3 - Article

SN - 0028-3908

VL - 56

SP - 692

EP - 701

JO - NEUROPHARMACOLOGY

JF - NEUROPHARMACOLOGY

IS - 3

ER -