Left entorhinal cortex and object recognition

Adele James, Tim von Oertzen, Ray Norbury, Hans-Juergen Huppertz, Kaz R Brandt

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Abstract

The present research explored the role of the medial temporal lobes in object memory in the unique patient MR, who has a selective lesion to her left lateral entorhinal cortex. Two experiments explored recognition memory for object identity and object location in MR and matched controls. The results showed that MR had intact performance in an object location task [MR=0.70, controls=0.69, t(6)=0.06, P>0.05], but was impaired in an object identity task [MR=0.62, controls=0.84, t(6)=−4.12, P<0.05]. No differences in correct recollection or familiarity emerged. These results suggest a differential role of the entorhinal cortex in object recognition memory. The current research is therefore the first patient study to show the role of the lateral entorhinal cortex in object identity recognition and suggests that current medial temporal lobe theoretical models on both object and recognition memory require atheoretical re-think to account for the contributions of the entorhinal cortex in these processes.


© 2018, Wolter Kluwer Helath, Inc. The attached document (embargoed until 21/03/2019) is an author produced version of a paper published in NEUROREPORT uploaded in accordance with the publisher’s self- archiving policy. The final published version(version of record) is available online at the link below. Some minor differences between this version and the final published version may remain. We suggest you refer to the final published version should you wish to cite from it.


Original languageEnglish
Pages (from-to)363–367
JournalNEUROREPORT
Volume29
Issue number5
DOIs
Publication statusPublished - 21 Mar 2018

Cite this

James, A., von Oertzen, T., Norbury, R., Huppertz, H-J., & Brandt, K. R. (2018). Left entorhinal cortex and object recognition. NEUROREPORT, 29(5), 363–367. https://doi.org/10.1097/WNR.0000000000000974