Neuroimaging Auditory Hallucinations in Schizophrenia:: From Neuroanatomy to Neurochemistry and Beyond

Paul Allen; Gemma Modinos; Daniela Hubl; Gregory Shields; Arnaud Cachia; Renaud Jardri; Pierre Thomas; Todd Woodward; Paul Shotbolt; Marion Plaze; Ralph Hoffman

doi:10.1093/schbul/sbs066

Neuroimaging Auditory Hallucinations in Schizophrenia: From Neuroanatomy to Neurochemistry and Beyond

Paul Allen, Gemma Modinos, Daniela Hubl, Gregory Shields, Arnaud Cachia, Renaud Jardri, Pierre Thomas, Todd Woodward, Paul Shotbolt, Marion Plaze, Ralph Hoffman

Research output: Contribution to journal › Article

Abstract

Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.

Original language	English
Pages (from-to)	695-703
Journal	SCHIZOPHRENIA BULLETIN
Volume	38
Issue number	4
DOIs	https://doi.org/10.1093/schbul/sbs066
Publication status	Published - 2012

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10.1093/schbul/sbs066

http://dx.doi.org/10.1093/schbul/sbs066

Cite this

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title = "Neuroimaging Auditory Hallucinations in Schizophrenia:: From Neuroanatomy to Neurochemistry and Beyond",

abstract = "Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.",

author = "Paul Allen and Gemma Modinos and Daniela Hubl and Gregory Shields and Arnaud Cachia and Renaud Jardri and Pierre Thomas and Todd Woodward and Paul Shotbolt and Marion Plaze and Ralph Hoffman",

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T1 - Neuroimaging Auditory Hallucinations in Schizophrenia:

T2 - From Neuroanatomy to Neurochemistry and Beyond

AU - Allen, Paul

AU - Modinos, Gemma

AU - Hubl, Daniela

AU - Shields, Gregory

AU - Cachia, Arnaud

AU - Jardri, Renaud

AU - Thomas, Pierre

AU - Woodward, Todd

AU - Shotbolt, Paul

AU - Plaze, Marion

AU - Hoffman, Ralph

PY - 2012

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N2 - Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.

AB - Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.

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DO - 10.1093/schbul/sbs066

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