Oestrogen:: Brain ageing, cognition and neuropsychiatric disorder

Ray Norbury; Michael Craig; William J Cutter; Malcolm Whitehead; Declan G M Murphy

doi:10.1258/1362180042003857

Oestrogen: Brain ageing, cognition and neuropsychiatric disorder

Ray Norbury, Michael Craig, William J Cutter, Malcolm Whitehead, Declan G M Murphy

School of Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of oestrogen on brain ageing, cognition and neuropsychiatric disorder are an important public health issue, which, despite intensive research, has yet to be resolved. Evidence from basic science demonstrates that oestrogen has multiple protective effects on neurons and neurotransmitter systems. However, the evidence for oestrogen having a clinical role in the treatment and prevention of neuropsychiatric disorders is not well established. Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool.

Original language	English
Pages (from-to)	118-22
Number of pages	5
Journal	The Journal of the British Menopause Society
Volume	10
Issue number	3
DOIs	https://doi.org/10.1258/1362180042003857
Publication status	Published - Sept 2004

Keywords

Aging
Alzheimer Disease
Brain
Depressive Disorder
Estrogen Replacement Therapy
Estrogens
Female
Humans
Schizophrenia

Access to Document

10.1258/1362180042003857

Cite this

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title = "Oestrogen:: Brain ageing, cognition and neuropsychiatric disorder",

abstract = "The effects of oestrogen on brain ageing, cognition and neuropsychiatric disorder are an important public health issue, which, despite intensive research, has yet to be resolved. Evidence from basic science demonstrates that oestrogen has multiple protective effects on neurons and neurotransmitter systems. However, the evidence for oestrogen having a clinical role in the treatment and prevention of neuropsychiatric disorders is not well established. Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool.",

keywords = "Aging, Alzheimer Disease, Brain, Depressive Disorder, Estrogen Replacement Therapy, Estrogens, Female, Humans, Schizophrenia",

author = "Ray Norbury and Michael Craig and Cutter, {William J} and Malcolm Whitehead and Murphy, {Declan G M}",

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AU - Norbury, Ray

AU - Craig, Michael

AU - Cutter, William J

AU - Whitehead, Malcolm

AU - Murphy, Declan G M

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AB - The effects of oestrogen on brain ageing, cognition and neuropsychiatric disorder are an important public health issue, which, despite intensive research, has yet to be resolved. Evidence from basic science demonstrates that oestrogen has multiple protective effects on neurons and neurotransmitter systems. However, the evidence for oestrogen having a clinical role in the treatment and prevention of neuropsychiatric disorders is not well established. Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool.

KW - Aging

KW - Alzheimer Disease

KW - Brain

KW - Depressive Disorder

KW - Estrogen Replacement Therapy

KW - Estrogens

KW - Female

KW - Humans

KW - Schizophrenia

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JO - The Journal of the British Menopause Society

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