TEMPORAL DYNAMICS OF MEMORY FORMATION IN THE VENTROLATERAL PREFRONTAL CORTEX INVESTIGATED THROUGH RTMS

Angela Medvedeva, Saw Rebecca, Giorgio Fuggetta, Giulia Galli

Research output: Contribution to conferencePoster

Abstract

For many years, scientists have believed that the crucial time for memory formation is when the to-be-remembered information is presented to us. However, recent research has demonstrated that the time-course of memory formation is far more multifaceted, and that brain activity immediately before the presentation of a to-be-remembered event, and immediately after its termination, is also relevant. In this experiment, we aim to characterize the role of brain activity that follows the termination of an event with repetitive Transcranial Magnetic Stimulation (rTMS). We administered 500 ms of 20 Hz rTMS over the left ventrolateral prefrontal cortex (VLPFC) at different points in time surrounding the presentation of visually presented words during encoding. We tested the effects of rTMS on the subsequent recognition of the words. The results showed that VLPFC rTMS applied in the time surrounding the offset of the words disrupted subsequent recognition accuracy. This finding supports the notion that brain mechaniss occurring in the left VLPFC after the offset of the stimulus are crucial for the formation of a new memory trace.

Keywords: episodic memory, long-term memory, memory encoding, rTMS
Original languageEnglish
Pages458-458
Number of pages1
Publication statusPublished - 1 Mar 2019
Event3rd International Brain Stimulation Conference, 24-27 February 2019, Vancouver Convention Center, Vancouver, Canada - Vancouver, Vancouver, Canada
Duration: 24 Feb 201927 Mar 2019
https://www.elsevier.com/events/conferences/international-brain-stimulation-conference

Conference

Conference3rd International Brain Stimulation Conference, 24-27 February 2019, Vancouver Convention Center, Vancouver, Canada
CountryCanada
CityVancouver
Period24/02/1927/03/19
Internet address

Cite this

Medvedeva, A., Rebecca, S., Fuggetta, G., & Galli, G. (2019). TEMPORAL DYNAMICS OF MEMORY FORMATION IN THE VENTROLATERAL PREFRONTAL CORTEX INVESTIGATED THROUGH RTMS. 458-458. Poster session presented at 3rd International Brain Stimulation Conference, 24-27 February 2019, Vancouver Convention Center, Vancouver, Canada, Vancouver, Canada.