The effects of storage conditions on long-chain polyunsaturated fatty acids, lipid mediators, and antioxidants in donor human milk – a review

Isabell Nessel, Minesh Khashu, Simon Dyall

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Donor human milk (DHM) is the preferred alternative for feeding infants, if maternal milk is not available. However, extensive storage and processing of DHM may negatively affect the composition. Currently safety measures predominantly consider microbiological aspects, and with the increasing demand for DHM in neonatal units due to greater survival of extremely preterm infants it is imperative to prioritise nutritional quality. This review summarises current evidence of the effects of storage and processing conditions on total fat, long-chain polyunsaturated fatty acids, lipid mediators and antioxidant content of DHM.
Based on the available evidence, it is recommended that storage time is minimised, and DHM kept in light protected bottles. Storage at 4°C should be avoided whenever possible, with storage at 80°C prior to pasteurisation being preferential. Further research is needed to evaluate the effects of long term storage at 20°C, and the impact of storage conditions on lipid mediators.

© 2019, Elsevier. The attached document (embargoed until 13/07/2020) is an author produced version of a paper published in PROSTAGLANDINS, LEUKOTRIENES AND ESSENTIAL FATTY ACIDS uploaded in accordance with the publisher’s self- archiving policy. The final published version (version of record) is available online at the link. Some minor differences between this version and the final published version may remain. We suggest you refer to the final published version should you wish to cite from it.
Original languageEnglish
JournalProstaglandins, leukotrienes, and essential fatty acids
Publication statusPublished - 13 Jul 2019

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